Repellent DEET is dangerous, there are fatal cases!

The results of researchers carried out by team of French physics of Angers University and Institute for Research and Development in Montpellier allow confirming that well known and widely spread repellent as DEET is dangerous for human health. During series of experiments with the nerve cells of insects and mammals the experts in France found that the preparation has the ability to block the action of an enzyme, regulating the transmission of nerve impulses.
 
As you know, the first time a repellent based on diethyl toluamide was developed in 1946 by order of the U.S. Army, who has attended to the protection of its troops from insects that perform in the tropical areas. Widespread throughout the world repellents with DEET (DEET) began in 1957 and now, according to the manufacturers of these drugs each year with approximately 200 million people from almost all over the glob.

Until recently it was believed that the principle of DEET limited by blocking of smell of blood-sucking insects, which deprives them of the ability to find their prey by smell. But now the French scientists found that the repellent effect on the nervous system can be much more serious and dangerous, and this applies not only to the blood-sucking insects, but also mammals.

The authors argue that the active component of repellent interacts directly with acetylcholinesterase (the enzyme responsible for the deactivation of the neurotransmitter acetylcholine) that returns nerve cells to normal state after transmission of the nerve impulse to muscle fibers. However, the interactions with acetylcholinesterase DEET lead to deactivation of a neurotransmitter that is not obtained and this, in turn, can ultimately lead to prolonged muscle spasm.

As medicine practice shows, for last few decades of observations in the United States territory  it have been documented cases of muscle spasms that are associated with excessive use of DEET. It must be said that there are cases where the muscle spasms led to the death of a person.